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A minimization principle for transition paths of maximum flux for collective variables

Considered is the construction of transition paths of conformational changes for proteins and other macromolecules, using methods that do not require the generation of dynamics trajectories. Special attention is given to the use of a reduced set of collective variables for describing such paths. A f...

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Bibliographic Details
Published in:Theor Chem Acc
Main Authors: Skeel, Robert D., Zhao, Ruijun, Post, Carol Beth
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5722035/
https://ncbi.nlm.nih.gov/pubmed/29225509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00214-016-2041-3
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