Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease

BACKGROUND: Genome‐wide association studies identified ADAMTS7 as a risk locus for coronary artery disease (CAD). Functional studies suggest that ADAMTS7 may promote cellular processes in atherosclerosis. We sought to examine the association between genetic variation at ADAMTS7 and measures of ather...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Chan, Kenneth, Pu, Xiangyuan, Sandesara, Pratik, Poston, Robin N., Simpson, Iain A., Quyyumi, Arshed A., Ye, Shu, Patel, Riyaz S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721775/
https://ncbi.nlm.nih.gov/pubmed/29089340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006928
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