Attenuated Superoxide Dismutase 2 Activity Induces Atherosclerotic Plaque Instability During Aging in Hyperlipidemic Mice

BACKGROUND: Atherosclerosis progression during aging culminates in the development of vulnerable plaques, which may increase the risk of cardiovascular events. Increased generation and/or decreased scavenging of reactive oxygen species in the vascular wall are major contributors to atherogenesis. We...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Vendrov, Aleksandr E., Stevenson, Mark D., Alahari, Samthosh, Pan, Hua, Wickline, Samuel A., Madamanchi, Nageswara R., Runge, Marschall S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721769/
https://ncbi.nlm.nih.gov/pubmed/29079564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006775
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