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Sofosbuvir‐based regimens for the treatment of chronic hepatitis C in severe renal dysfunction
Sofosbuvir (SOF) is a nonstructural 5B polymerase inhibitor with activity in all hepatitis C virus (HCV) genotypes and is the backbone of many anti‐HCV drug regimens. SOF is converted into inactive metabolites that undergo renal excretion. Patients with an estimated glomerular filtration rate (eGFR)...
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| Publicat a: | Hepatol Commun |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5721450/ https://ncbi.nlm.nih.gov/pubmed/29404457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1035 |
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