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Clinical endpoints and adaptive clinical trials in precirrhotic nonalcoholic steatohepatitis: Facilitating development approaches for an emerging epidemic

Due to the increasing prevalence of nonalcoholic steatohepatitis (NASH) and its associated health burden, there is a high need to develop therapeutic strategies for patients with this disease. Unfortunately, its long and asymptomatic natural history, the uncertainties about disease progression, the...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Filozof, Claudia, Chow, Shein‐Chung, Dimick‐Santos, Lara, Chen, Yeh‐Fong, Williams, Richard N., Goldstein, Barry J., Sanyal, Arun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721443/
https://ncbi.nlm.nih.gov/pubmed/29404480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1079
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