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Long-Term Follow-Up of Cardiac Function and Quality of Life for Patients in NSABP Protocol B-31/NRG Oncology: A Randomized Trial Comparing the Safety and Efficacy of Doxorubicin and Cyclophosphamide (AC) Followed by Paclitaxel With AC Followed by Paclitaxel and Trastuzumab in Patients With Node-Positive Breast Cancer With Tumors Overexpressing Human Epidermal Growth Factor Receptor 2

PURPOSE: Early cardiac toxicity is a risk associated with adjuvant chemotherapy plus trastuzumab. However, objective measures of cardiac function and health-related quality of life are lacking in long-term follow-up of patients who remain cancer free after completion of adjuvant treatment. PATIENTS...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Principais autores: Ganz, Patricia A., Romond, Edward H., Cecchini, Reena S., Rastogi, Priya, Geyer, Charles E., Swain, Sandra M., Jeong, Jong-Hyeon, Fehrenbacher, Louis, Gross, Howard M., Brufsky, Adam M., Flynn, Patrick J., Wahl, Tanya A., Seay, Thomas E., Wade, James L., Biggs, David D., Atkins, James N., Polikoff, Jonathan, Zapas, John L., Mamounas, Eleftherios P., Wolmark, Norman
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721228/
https://ncbi.nlm.nih.gov/pubmed/29072977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.74.1165
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