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Etiology and pathogenesis of the Marfan syndrome: current understanding

Much has changed regarding Marfan syndrome (MFS) over the past few decades. Once described solely as a heritable disorder of connective tissue, MFS is now one of a number of conditions recognized to be a disorder of abnormal signalling in the TGF-β pathway. The cardinal features of MFS, once encompa...

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Dades bibliogràfiques
Publicat a:Ann Cardiothorac Surg
Autor principal: Pyeritz, Reed E.
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721105/
https://ncbi.nlm.nih.gov/pubmed/29270371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/acs.2017.10.04
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