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Estimating virus effective population size and selection without neutral markers

By combining high-throughput sequencing (HTS) with experimental evolution, we can observe the within-host dynamics of pathogen variants of biomedical or ecological interest. We studied the evolutionary dynamics of five variants of Potato virus Y (PVY) in 15 doubled-haploid lines of pepper. All plant...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Rousseau, Elsa, Moury, Benoît, Mailleret, Ludovic, Senoussi, Rachid, Palloix, Alain, Simon, Vincent, Valière, Sophie, Grognard, Frédéric, Fabre, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720836/
https://ncbi.nlm.nih.gov/pubmed/29155894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006702
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