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Flip/flop mating-type switching in the methylotrophic yeast Ogataea polymorpha is regulated by an Efg1-Rme1-Ste12 pathway

In haploid cells of Ogataea (Hansenula) polymorpha an environmental signal, nitrogen starvation, induces a reversible change in the structure of a chromosome. This process, mating-type switching, inverts a 19-kb DNA region to place either MATa or MATα genes under centromeric repression of transcript...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Hanson, Sara J., Byrne, Kevin P., Wolfe, Kenneth H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720833/
https://ncbi.nlm.nih.gov/pubmed/29176810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007092
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