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Pred-hERG: A Novel web-Accessible Computational Tool for Predicting Cardiac Toxicity

The blockage of the hERG K(+) channels is closely associated with lethal cardiac arrhythmia. The notorious ligand promiscuity of this channel earmarked hERG as one of the most important antitargets to be considered in early stages of drug development process. Herein we report on the development of a...

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Detalhes bibliográficos
Publicado no:Mol Inform
Main Authors: Braga, Rodolpho C., Alves, Vinicius M., Silva, Meryck F. B., Muratov, Eugene, Fourches, Denis, Lião, Luciano M., Tropsha, Alexander, Andrade, Carolina H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720373/
https://ncbi.nlm.nih.gov/pubmed/27490970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201500040
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