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Pred-hERG: A Novel web-Accessible Computational Tool for Predicting Cardiac Toxicity

The blockage of the hERG K(+) channels is closely associated with lethal cardiac arrhythmia. The notorious ligand promiscuity of this channel earmarked hERG as one of the most important antitargets to be considered in early stages of drug development process. Herein we report on the development of a...

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Publicat a:Mol Inform
Autors principals: Braga, Rodolpho C., Alves, Vinicius M., Silva, Meryck F. B., Muratov, Eugene, Fourches, Denis, Lião, Luciano M., Tropsha, Alexander, Andrade, Carolina H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720373/
https://ncbi.nlm.nih.gov/pubmed/27490970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201500040
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