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EMT, CSCs, and drug resistance: the mechanistic link and clinical implications
The success of anticancer therapy is usually limited by the development of drug resistance. Such acquired resistance is driven, in part, by intratumoural heterogeneity — that is, the phenotypic diversity of cancer cells co-inhabiting a single tumour mass. The introduction of the cancer stem cell (CS...
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| Pubblicato in: | Nat Rev Clin Oncol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5720366/ https://ncbi.nlm.nih.gov/pubmed/28397828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2017.44 |
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