Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever

There are no approved treatments for Lassa fever, which is endemic to the same regions of West Africa that were recently devastated by Ebola. Here we show that a combination of human monoclonal antibodies that cross-react with the glycoproteins of all four clades of Lassa virus is able to rescue 100...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Mire, Chad E, Cross, Robert W, Geisbert, Joan B, Borisevich, Viktoriya, Agans, Krystle N, Deer, Daniel J, Heinrich, Megan L, Rowland, Megan M, Goba, Augustine, Momoh, Mambu, Boisen, Mathew L, Grant, Donald S, Fullah, Mohamed, Khan, Sheik Humarr, Fenton, Karla A, Robinson, James E, Branco, Luis M, Garry, Robert F, Geisbert, Thomas W
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719877/
https://ncbi.nlm.nih.gov/pubmed/28869611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4396
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