Generation of stable PDX derived cell lines using conditional reprogramming

Efforts to develop effective cancer therapeutics have been hindered by a lack of clinically predictive preclinical models which recapitulate this complex disease. Patient derived xenograft (PDX) models have emerged as valuable tools for translational research but have several practical limitations i...

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Vydáno v:Mol Cancer
Hlavní autoři: Borodovsky, Alexandra, McQuiston, Travis J., Stetson, Daniel, Ahmed, Ambar, Whitston, David, Zhang, Jingwen, Grondine, Michael, Lawson, Deborah, Challberg, Sharon S., Zinda, Michael, Pollok, Brian A., Dougherty, Brian A., D’Cruz, Celina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Letter to the Editor
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719579/
https://ncbi.nlm.nih.gov/pubmed/29212548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0745-1
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