Active-site plasticity revealed in the asymmetric dimer of AnPrx6 the 1-Cys peroxiredoxin and molecular chaperone from Anabaena sp. PCC 7120

Peroxiredoxins (Prxs) are vital regulators of intracellular reactive oxygen species levels in all living organisms. Their activity depends on one or two catalytically active cysteine residues, the peroxidatic Cys (C(P)) and, if present, the resolving Cys (C(R)). A detailed catalytic cycle has been d...

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Publicado no:Sci Rep
Main Authors: Mishra, Yogesh, Hall, Michael, Locmelis, Roland, Nam, Kwangho, Söderberg, Christopher A. G., Storm, Patrik, Chaurasia, Neha, Rai, Lal Chand, Jansson, Stefan, Schröder, Wolfgang P., Sauer, Uwe H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719442/
https://ncbi.nlm.nih.gov/pubmed/29215017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17044-3
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