Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD(+), for enhancing the production of 3-hydroxypropionic acid

3-Hydroxypropionic acid (3-HP) can be produced via the biological route involving two enzymatic reactions: dehydration of glycerol to 3-hydroxypropanal (3-HPA) and then oxidation to 3-HP. However, commercial production of 3-HP using recombinant microorganisms has been hampered with several problems,...

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Publicado no:Sci Rep
Main Authors: Park, Ye Seop, Choi, Un Jong, Nam, Nguyen Hoai, Choi, Sang Jin, Nasir, Abdul, Lee, Sun-Gu, Kim, Kyung Jin, Jung, Gyoo Yeol, Choi, Sangdun, Shim, Jeung Yeop, Park, Sunghoon, Yoo, Tae Hyeon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719400/
https://ncbi.nlm.nih.gov/pubmed/29214999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15400-x
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