Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care

INTRODUCTION: Statins are effective at preventing cardiovascular disease, widely prescribed and their use is growing. Uncertainty persists about whether they cause symptomatic muscle adverse effects, such as pain and weakness, in the absence of statin myopathy. Discrepancies between data from observ...

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Pubblicato in:BMJ Open
Autori principali: Herrett, Emily, Williamson, Elizabeth, Beaumont, Danielle, Prowse, Danielle, Youssouf, Nabila, Brack, Kieran, Armitage, Jane, Goldacre, Ben, MacDonald, Thomas, van Staa, Tjeerd, Roberts, Ian, Shakur-Still, Haleema, Smeeth, Liam
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2017
Soggetti:
Cardiovascular Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719321/
https://ncbi.nlm.nih.gov/pubmed/29197834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-016604
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