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Overexpression of microRNA-722 fine-tunes neutrophilic inflammation by inhibiting Rac2 in zebrafish

Neutrophilic inflammation is essential for defending against invading pathogens, but can also be detrimental in many clinical settings. The hematopoietic-specific small Rho-GTPase Rac2 regulates multiple pathways that are essential for neutrophil activation, including adhesion, migration, degranulat...

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Podrobná bibliografie
Vydáno v:Dis Model Mech
Hlavní autoři: Hsu, Alan Y., Wang, Decheng, Gurol, Theodore, Zhou, Wenqing, Zhu, Xiaoguang, Lu, Hsiu-Yi, Deng, Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719257/
https://ncbi.nlm.nih.gov/pubmed/28954734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.030791
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