The African Zika virus MR-766 is more virulent and causes more severe brain damage than current Asian lineage and dengue virus

The Zika virus (ZIKV) has two lineages, Asian and African, and their impact on developing brains has not been compared. Dengue virus (DENV) is a close family member of ZIKV and co-circulates with ZIKV. Here, we performed intracerebral inoculation of embryonic mouse brains with dengue virus 2 (DENV2)...

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Publicado en:Development
Autores principales: Shao, Qiang, Herrlinger, Stephanie, Zhu, Ya-Nan, Yang, Mei, Goodfellow, Forrest, Stice, Steven L., Qi, Xiao-Peng, Brindley, Melinda A., Chen, Jian-Fu
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719247/
https://ncbi.nlm.nih.gov/pubmed/28993398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.156752
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