Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1

Phosphoglycerate mutase 1 (PGAM1), an important enzyme in glycolysis, is overexpressed in a number of human cancers, thus has been proposed as a promising metabolic target for cancer treatments. The C-terminal portion of the available crystal structures of PGAM1 and its homologous proteins is partia...

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Liu, Shi-en, Hu, Jun-chi, Zhang, Hao, Xu, Pan, Wan, Wei, Zheng, Ming-yue, Yu, Kun-qian, Ding, Hong, Jiang, Hua-liang, Zhou, Lu, Luo, Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719155/
https://ncbi.nlm.nih.gov/pubmed/28748916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.37
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