Hispidulin mediates apoptosis in human renal cell carcinoma by inducing ceramide accumulation

Hispidulin, a polyphenolic flavonoid extracted from the traditional Chinese medicinal plant S involucrata, exhibits anti-tumor effects in a wide array of human cancer cells, mainly through growth inhibition, apoptosis induction and cell cycle arrest. However, its precise anticancer mechanisms remain...

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Bibliografiske detaljer
Udgivet i:Acta Pharmacol Sin
Main Authors: Gao, Hui, Gao, Ming-quan, Peng, Jian-jun, Han, Mei, Liu, Kai-li, Han, Yan-tao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719151/
https://ncbi.nlm.nih.gov/pubmed/29119970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.154
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