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Treatment of melanoma with selected inhibitors of signaling kinases effectively reduces proliferation and induces expression of cell cycle inhibitors

Cancer treatment often tends to involve direct targeting enzymes essential for the growth and proliferation of cancer cells. The aim of this study was the recognition of the possible role of selected protein kinases: PI3K, ERK1/2, and mTOR in cell proliferation and cell cycle in malignant melanoma....

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Detalhes bibliográficos
Publicado no:Med Oncol
Main Authors: Ciołczyk-Wierzbicka, Dorota, Gil, Dorota, Laidler, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719123/
https://ncbi.nlm.nih.gov/pubmed/29214525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-017-1069-0
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