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Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia

Glucocorticoid replacement therapy is the mainstay of treatment for congenital adrenal hyperplasia (CAH) but has a narrow therapeutic index and dose optimisation is challenging. Metabolomic profiling was carried out on plasma samples from 117 adults with 21-hydroxylase deficiency receiving their usu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alwashih, Mohammad A., Watson, David G., Andrew, Ruth, Stimson, Roland H., Alossaimi, Manal, Blackburn, Gavin, Walker, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719028/
https://ncbi.nlm.nih.gov/pubmed/29213133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17220-5
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