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Complement 5a Receptor deficiency does not influence adverse cardiac remodeling after pressure-overload in mice

Hypertension is one of the most common risk factors for the development heart failure in the general population. Inflammation plays a central role in this adverse remodeling and eventually to the development of heart failure. Circulating levels of Complement factor 5a (C5a) are increased in hyperten...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: de Haan, Judith J., Bosch, Lena, Borgman, Anouska, Bastemeijer, Marissa, Brans, Maike A. D., van de Weg, Sander M., de Kleijn, Dominique P. V., Sluijter, Joost P. G., el Azzouzi, Hamid, de Jager, Saskia C. A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719022/
https://ncbi.nlm.nih.gov/pubmed/29213128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16957-3
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