Complement 5a Receptor deficiency does not influence adverse cardiac remodeling after pressure-overload in mice

Hypertension is one of the most common risk factors for the development heart failure in the general population. Inflammation plays a central role in this adverse remodeling and eventually to the development of heart failure. Circulating levels of Complement factor 5a (C5a) are increased in hyperten...

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Bibliographic Details
Published in:Sci Rep
Main Authors: de Haan, Judith J., Bosch, Lena, Borgman, Anouska, Bastemeijer, Marissa, Brans, Maike A. D., van de Weg, Sander M., de Kleijn, Dominique P. V., Sluijter, Joost P. G., el Azzouzi, Hamid, de Jager, Saskia C. A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719022/
https://ncbi.nlm.nih.gov/pubmed/29213128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16957-3
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