Emulating a target trial of antiretroviral therapy regimens started before conception and risk of adverse birth outcomes

OBJECTIVE: To compare the effect of pre-conception initiation of zidovudine, lamivudine, nevirapine (ZDV/3TC/NVP) versus tenofovir, emtricitabine, efavirenz (TDF/FTC/EFV) on adverse birth outcomes. DESIGN: Emulation of a hypothetical (target) trial using a birth surveillance study in Botswana during...

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Publicado en:AIDS
Autores principales: CANIGLIA, Ellen C., ZASH, Rebecca, JACOBSON, Denise L., DISEKO, Modiegi, MAYONDI, Gloria, LOCKMAN, Shahin, CHEN, Jennifer, MMALANE, Mompati, MAKHEMA, Joseph, HERNÁN, Miguel A., SHAPIRO, Roger L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718935/
https://ncbi.nlm.nih.gov/pubmed/29112066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001673
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