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Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data
Immune cells infiltrating tumors can have important impact on tumor progression and response to therapy. We present an efficient algorithm to simultaneously estimate the fraction of cancer and immune cell types from bulk tumor gene expression data. Our method integrates novel gene expression profile...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5718706/ https://ncbi.nlm.nih.gov/pubmed/29130882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26476 |
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