Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER

CONTEXT: Estrogens affect the incidence and progression of colorectal cancer (CRC), although the precise molecular mechanisms remain ill-defined. OBJECTIVE: The present study investigated prereceptor estrogen metabolism through steroid sulphatase (STS) and 17β-hydroxysteroid dehydrogenase activity a...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Gilligan, Lorna C., Rahman, Habibur P., Hewitt, Anne-Marie, Sitch, Alice J., Gondal, Ali, Arvaniti, Anastasia, Taylor, Angela E., Read, Martin L., Morton, Dion G., Foster, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718700/
https://ncbi.nlm.nih.gov/pubmed/28945888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-3716
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