Updated analysis of CALGB 100104 (Alliance): a randomised phase III study evaluating lenalidomide vs placebo maintenance after single autologous stem cell transplant for multiple myeloma

BACKGROUND: CALGB 100104 (Alliance) studied lenalidomide vs. placebo following autologous stem cell transplant (ASCT) for newly diagnosed myeloma patients, demonstrating improved time to progression (TTP) and overall survival (OS), and an increase in second primary malignancies (SPM) for lenalidomid...

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Udgivet i:Lancet Haematol
Main Authors: Holstein, Sarah A., Jung, Sin-Ho, Richardson, Paul G., Hofmeister, Craig C., Hurd, David D., Hassoun, Hani, Giralt, Sergio, Stadtmauer, Edward A., Weisdorf, Daniel J., Vij, Ravi, Moreb, Jan S., Callander, Natalie S., van Besien, Koen, Gentile, Teresa G., Isola, Luis, Maziarz, Richard T, Bashey, Asad, Landau, Heather, Martin, Thomas, Qazilbash, Muzaffar H, Rodriguez, Cesar, McClune, Brian, Schlossman, Robert L., Smith, Scott E., Hars, Vera, Owzar, Kouros, Jiang, Chen, Boyd, Molly, Schultz, Chelsea, Wilson, Marcia, Hari, Parameswaran, Pasquini, Marcelo C., Horowitz, Mary M., Shea, Thomas C., Devine, Steven M., Linker, Charles, Anderson, Kenneth C., McCarthy, Philip L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718627/
https://ncbi.nlm.nih.gov/pubmed/28826616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(17)30140-0
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