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Investigating endogenous µ-opioid receptors in human keratinocytes as pharmacological targets using novel fluorescent ligand

Opioids in skin function during stress response, regeneration, ageing and, particularly in regulating sensation. In chronic pruritus, topical treatment with Naltrexone changes μ-opioid receptor (μ-OR) localization to relieve itch. The molecular mechanisms behind the effects of Naltrexone on μ-OR fun...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Leong, Cheryl, Neumann, Christine, Ramasamy, Srinivas, Rout, Bhimsen, Yi Wee, Lim, Bigliardi-Qi, Mei, Bigliardi, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718609/
https://ncbi.nlm.nih.gov/pubmed/29211767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188607
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