A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients

Hypertriglyceridemia is recognized as an independent risk factor for coronary artery disease. The apolipoprotein A5 gene (APOA5) is a key regulator of triglyceride levels. We aimed to evaluate the associations of single nucleotide polymorphisms (SNPs) in APOA5, including -1131T>C and c.553G>T,...

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Vydáno v:PLoS One
Hlavní autoři: Kim, Minjoo, Kim, Minkyung, Yoo, Hye Jin, Lee, Eunji, Chae, Jey Sook, Lee, Sang-Hyun, Lee, Jong Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718602/
https://ncbi.nlm.nih.gov/pubmed/29211729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186693
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