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A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients

Hypertriglyceridemia is recognized as an independent risk factor for coronary artery disease. The apolipoprotein A5 gene (APOA5) is a key regulator of triglyceride levels. We aimed to evaluate the associations of single nucleotide polymorphisms (SNPs) in APOA5, including -1131T>C and c.553G>T,...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kim, Minjoo, Kim, Minkyung, Yoo, Hye Jin, Lee, Eunji, Chae, Jey Sook, Lee, Sang-Hyun, Lee, Jong Ho
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718602/
https://ncbi.nlm.nih.gov/pubmed/29211729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186693
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