How well do you know your mutation? Complex effects of genetic background on expressivity, complementation, and ordering of allelic effects

For a given gene, different mutations influence organismal phenotypes to varying degrees. However, the expressivity of these variants not only depends on the DNA lesion associated with the mutation, but also on factors including the genetic background and rearing environment. The degree to which the...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Chandler, Christopher H., Chari, Sudarshan, Kowalski, Alycia, Choi, Lin, Tack, David, DeNieu, Michael, Pitchers, William, Sonnenschein, Anne, Marvin, Leslie, Hummel, Kristen, Marier, Christian, Victory, Andrew, Porter, Cody, Mammel, Anna, Holms, Julie, Sivaratnam, Gayatri, Dworkin, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718557/
https://ncbi.nlm.nih.gov/pubmed/29166655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007075
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