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Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood

Dendritic cells (DC) are potent antigen-presenting cells that initiate and regulate T-cell responses. In this study, the numbers and functional cytokine secretions of plasmacytoid and myeloid DC (pDC and mDC, respectively) in peripheral blood from young and elderly subjects were compared. Overall, p...

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Detalhes bibliográficos
Publicado no:Hum Immunol
Main Authors: Jing, Yu, Shaheen, Elias, Drake, Richard R., Chen, Nianyong, Gravenstein, Stefan, Deng, Yuping
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718338/
https://ncbi.nlm.nih.gov/pubmed/19596035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2009.07.005
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