Proteolytic Degradation and Inflammation Play Critical Roles in Polypoidal Choroidal Vasculopathy

Polypoidal choroidal vasculopathy (PCV) is a common subtype of wet age-related macular degeneration in Asian populations, whereas choroidal neovascularization is the typical subtype in Western populations. The cause of PCV is unknown. By comparing the phenotype of a PCV mouse model expressing protea...

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Publicado en:Am J Pathol
Autores principales: Kumar, Sandeep, Nakashizuka, Hiroyuki, Jones, Alex, Lambert, Alyssia, Zhao, Xuchen, Shen, Megan, Parker, Mackenzie, Wang, Shixian, Berriochoa, Zachary, Fnu, Amrita, VanBeuge, Stephanie, Chévez-Barrios, Patricia, Tso, Mark, Rainier, Jon, Fu, Yingbin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718105/
https://ncbi.nlm.nih.gov/pubmed/28941979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.025
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