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IKKβ Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis
In the immature lung, inflammation and injury disrupt the epithelial–mesenchymal interactions required for normal development. Innate immune signaling and NF-κB activation disrupt the normal expression of multiple mesenchymal genes that play a key role in airway branching and alveolar formation. To...
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| Publicado no: | Am J Pathol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5718091/ https://ncbi.nlm.nih.gov/pubmed/28923684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.08.013 |
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