Free-Water Improves Detection of Changes in the Substantia Nigra in Parkinsonism: A Multi-Site Study

BACKGROUND: Imaging markers that are sensitive to parkinsonism across multiple sites are critically needed for clinical trials. OBJECTIVE: To evaluate changes in the substantia nigra using single- and bi-tensor models of diffusion magnetic resonance imaging in PD, MSA, and PSP. METHODS: The study co...

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Publicado no:Mov Disord
Main Authors: Ofori, Edward, Krismer, Florian, Burciu, Roxana G., Pasternak, Ofer, McCracken, Johanna L., Lewis, Mechelle M., Du, Guangwei, McFarland, Nikolaus R., Okun, Michael S., Poewe, Werner, Mueller, Christoph, Gizewski, Elke R., Schocke, Michael, Kremser, Christian, Li, Hong, Huang, Xuemei, Seppi, Klaus, Vaillancourt, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5718046/
https://ncbi.nlm.nih.gov/pubmed/28714593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27100
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