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Study on orally delivered paclitaxel nanocrystals: modification, characterization and activity in the gastrointestinal tract

Drug nanocrystals (NCs) can improve the solubility and bioavailability of insoluble drugs for oral administration. However, the biocompatibility and mechanisms of transmittance of drug NCs through the intestinal epithelial tissue are still not well understood. In this work, the physico-chemical prop...

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Detalhes bibliográficos
Publicado no:R Soc Open Sci
Main Authors: Liu, Runcong, Chang, Ya-Nan, Xing, Gengmei, Li, Min, Zhao, Yuliang
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717641/
https://ncbi.nlm.nih.gov/pubmed/29291067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.170753
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