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An apoptosis-driven ‘onco-regenerative niche’: roles of tumour-associated macrophages and extracellular vesicles

The cell-death programme, apoptosis, is well established as a tumour suppressor mechanism. Paradoxically, high levels of apoptosis in tumours are closely coupled with poor prognosis. Indeed, where it has been studied, cell loss is a striking feature of high-grade cancers, illustrating the importance...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: Gregory, Christopher D., Paterson, Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717442/
https://ncbi.nlm.nih.gov/pubmed/29158317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0003
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