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Hunting for the mutant without the MAP(K)
In a paper recently published in Cell Research, Yu et al. identify two MAPK-related kinases, MAPK11 and HIPK3, as positive regulators of levels of mutant huntingtin protein, a toxic species highly involved in Huntington's disease (HD) pathology. The identification and validation of these kinase...
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| Gepubliceerd in: | Cell Res |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5717406/ https://ncbi.nlm.nih.gov/pubmed/29134957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.140 |
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