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Network dynamics-based cancer panel stratification for systemic prediction of anticancer drug response

Cancer is a complex disease involving multiple genomic alterations that disrupt the dynamic response of signaling networks. The heterogeneous nature of cancer, which results in highly variable drug response, is a major obstacle to developing effective cancer therapy. Previous studies of cancer thera...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Choi, Minsoo, Shi, Jue, Zhu, Yanting, Yang, Ruizhen, Cho, Kwang-Hyun
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717260/
https://ncbi.nlm.nih.gov/pubmed/29208897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02160-5
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