Development and Qualification of an Opsonophagocytic Killing Assay To Assess Immunogenicity of a Bioconjugated Escherichia coli Vaccine

The global burden of disease caused by extraintestinal pathogenic Escherichia coli (ExPEC) is increasing as the prevalence of multidrug-resistant strains rises. A multivalent ExPEC O-antigen bioconjugate vaccine could have a substantial impact in preventing bacteremia and urinary tract infections. D...

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Publicat a:Clin Vaccine Immunol
Autors principals: Abbanat, Darren, Davies, Todd A., Amsler, Karen, He, Wenping, Fae, Kellen, Janssen, Sarah, Poolman, Jan T., van den Dobbelsteen, Germie P. J. M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717180/
https://ncbi.nlm.nih.gov/pubmed/28971965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00123-17
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