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Establishment of a strain of haemophilia-A pigs by xenografting of foetal testicular tissue from neonatally moribund cloned pigs

Grafting of testicular tissue into immunodeficient mice makes it possible to obtain functional sperm from immature donor animals that cannot be used for reproduction. We have developed a porcine model of human haemophilia A (haemophilia-A pigs) by nuclear transfer cloning from foetal fibroblasts aft...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kaneko, Hiroyuki, Kikuchi, Kazuhiro, Nakai, Michiko, Fuchimoto, Daiichiro, Suzuki, Shunichi, Sembon, Shoichiro, Noguchi, Junko, Onishi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717049/
https://ncbi.nlm.nih.gov/pubmed/29208927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17017-6
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