Early genetic aberrations in patients with sporadic colorectal cancer

Chromosome instability (CIN) is widely observed in both sporadic and hereditary colorectal cancer (CRC). Defects in APC and WNT signaling are primarily associated with CIN in hereditary CRC, but the genetic causes for CIN in sporadic CRC remain elusive. Using high-density SNP array and exome data fr...

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Veröffentlicht in:Mol Carcinog
Hauptverfasser: Druliner, Brooke R., Ruan, Xiaoyang, Sicotte, Hugues, O’Brien, Daniel, Liu, Hongfang, Kocher, Jean-Pierre A., Boardman, Lisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716916/
https://ncbi.nlm.nih.gov/pubmed/28926134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22738
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