Procyanidin B2 3,3″-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK

Neoplastic cells exhibit higher oxidative stress compared to normal cells; however, antioxidants based clinical trials have mostly failed. Another attractive therapeutic approach is to further increase the oxidative stress in cancer cells leading to cell death. Herein, we show that Procyanidin B2 3,...

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Detalles Bibliográficos
Publicado en:Mol Carcinog
Main Authors: Kumar, Rahul, Deep, Gagan, Wempe, Michael F., Surek, Joseph, Kumar, Amit, Agarwal, Rajesh, Agarwal, Chapla
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716889/
https://ncbi.nlm.nih.gov/pubmed/28876465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22731
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