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Routine Use of Clinical Exome-Based Next Generation Sequencing for Evaluation of Patients with Thrombotic Microangiopathies

Next-generation sequencing is increasingly used for clinical evaluation of patients presenting with thrombotic microangiopathies because it allows for simultaneous interrogation of multiple complement and coagulation pathway genes known to be associated with disease. However, the diagnostic yield is...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Gaut, Joseph P., Jain, Sanjay, Pfeifer, John D., Vigh-Conrad, Katinka A., Corliss, Meagan, Sharma, Mukesh K., Heusel, Jonathan W., Cottrell, Catherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716882/
https://ncbi.nlm.nih.gov/pubmed/28752844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2017.90
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