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Task-evoked pupil dilation and BOLD variance as indicators of locus coeruleus dysfunction

Pupillary responses during cognitive tasks are linked to functioning of the locus coeruleus (LC). The LC is an early site of abnormal tau deposition, which may contribute to key aspects of Alzheimer’s disease (AD) pathophysiology. We previously found attenuation of pupillary responses to increases i...

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Detalhes bibliográficos
Publicado no:Cortex
Main Authors: Elman, Jeremy A., Panizzon, Matthew S., Hagler, Donald J., Eyler, Lisa T., Granholm, Eric L., Fennema-Notestine, Christine, Lyons, Michael J., McEvoy, Linda K., Franz, Carol E., Dale, Anders M., Kremen, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716879/
https://ncbi.nlm.nih.gov/pubmed/29096196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cortex.2017.09.025
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