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Transforming growth factor β-induced epithelial to mesenchymal transition requires the Ste20-like kinase SLK independently of its catalytic activity

Invasion can be stimulated in vitro using the soluble ligand transforming growth factor-β (TGFβ) to induce a process called epithelial-to-mesenchymal transition (EMT) characterized by cell-cell junction breakdown and an invasive phenotype. We have previously demonstrated a role for Ste20-like kinase...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Conway, Jillian, Al-Zahrani, Khalid N., Pryce, Benjamin R., Abou-Hamad, John, Sabourin, Luc A.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716764/
https://ncbi.nlm.nih.gov/pubmed/29228724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21928
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