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Altered follicular helper T cell impaired antibody production in a murine model of myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic diseases which have a high risk of progressing to acute myeloid leukemia. MDS patients have immunologic deficiency, including T and B cells dysfunction. Follicular T helper cells (Tfh, CD4(+)CXCR5(+)) are an important subset of help...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jiang, Huijuan, Cui, Ningbo, Yang, Liyan, Liu, Chunyan, Yue, Lanzhu, Guo, Lifang, Wang, Huaquan, Shao, Zonghong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716728/
https://ncbi.nlm.nih.gov/pubmed/29228688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21548
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