Limit of Detection and Threshold for Positivity of the Centers for Disease Control and Prevention Assay for Factor VIII Inhibitors

BACKGROUND: The Bethesda assay (BA) for measurement of factor VIII (FVIII) inhibitors called for quantitation of positive inhibitors using dilutions producing 25–75% residual activity (RA), corresponding to 0.4–2.0 Bethesda units, recommending use of “more sensitive methods” for samples with RA clos...

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Vydáno v:J Thromb Haemost
Hlavní autoři: Miller, Connie H., Boylan, Brian, Shapiro, Amy D., Lentz, Steven R., Wicklund, Brian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716470/
https://ncbi.nlm.nih.gov/pubmed/28795528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13795
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