Ectopic expression of Pax4 in pancreatic δ cells results in β-like cell neogenesis

The recent demonstration that pancreatic α cells can be continuously regenerated and converted into β-like cells upon ectopic expression of Pax4 opened new avenues of research in the endocrine cell differentiation and diabetes fields. To determine whether such plasticity was also shared by δ cells,...

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Publicado en:J Cell Biol
Autores principales: Druelle, Noémie, Vieira, Andhira, Shabro, Aidin, Courtney, Monica, Mondin, Magali, Rekima, Samah, Napolitano, Tiziana, Silvano, Serena, Navarro-Sanz, Sergi, Hadzic, Biljana, Avolio, Fabio, Rassoulzadegan, Minoo, Schmid, Herbert A., Mansouri, Ahmed, Collombat, Patrick
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716283/
https://ncbi.nlm.nih.gov/pubmed/29025873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201704044
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