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Membrane curvature directs the localization of Cdc42p to novel foci required for cell–cell fusion

Cell fusion is ubiquitous in eukaryotic fertilization and development. The highly conserved Rho–GTPase Cdc42p promotes yeast fusion through interaction with Fus2p, a pheromone-induced amphiphysin-like protein. We show that in prezygotes, Cdc42p forms a novel Fus2p-dependent focus at the center of th...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Smith, Jean A., Hall, Allison E., Rose, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716282/
https://ncbi.nlm.nih.gov/pubmed/29066609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703169
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