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Membrane curvature directs the localization of Cdc42p to novel foci required for cell–cell fusion

Cell fusion is ubiquitous in eukaryotic fertilization and development. The highly conserved Rho–GTPase Cdc42p promotes yeast fusion through interaction with Fus2p, a pheromone-induced amphiphysin-like protein. We show that in prezygotes, Cdc42p forms a novel Fus2p-dependent focus at the center of th...

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Vydáno v:J Cell Biol
Hlavní autoři: Smith, Jean A., Hall, Allison E., Rose, Mark D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716282/
https://ncbi.nlm.nih.gov/pubmed/29066609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703169
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